Anti-proliferative Effect of Licochalcone A on Vascular Smooth Muscle Cells

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Anti-proliferative effect of licochalcone A on vascular smooth muscle cells.

Licochalcone A, a flavonoid found in licorice root (Glycyrrhiza glabra), is known for its anti-microbial activity and its reported ability to inhibit cancer cell proliferation. In the present study, we investigated whether licochalcone A inhibits rat vascular smooth muscle cell (rVSMC) proliferation. Our data indicate that 5 microM licochalcone A inhibited platelet-derived growth factor (PDGF)-...

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ژورنال

عنوان ژورنال: Biological and Pharmaceutical Bulletin

سال: 2008

ISSN: 0918-6158,1347-5215

DOI: 10.1248/bpb.31.1996